Rebus Biosystems Partners with ROSALIND to Co-Develop Spatial Omics Software

SANTA CLARA, Calif. & SAN DIEGO–(BUSINESS WIRE)–Rebus Biosystems Inc, (“Rebus Bio”, “Rebus”), an Illumina Ventures-backed life science technology company creating revolutionary tools to advance spatial omics research, announced today it is partnering with Rosalind, Inc. to co-develop new spatial omics software. The technology will democratize data from single cell spatial analyses from the Rebus Esper™ […]

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Rebus Biosystems Expands Scientific Advisory Board with Key Appointments

SANTA CLARA, CA – March 17, 2022 – Rebus Biosystems Inc, (“Rebus Bio”, “Rebus”), an Illumina Ventures-backed life science technology company creating revolutionary tools to advance spatial omics research, announced today that Arnold Kriegstein, M.D., PhD. and Kun Zhang, PhD., have been appointed to the Company’s Scientific Advisory Board (SAB). Both Drs. Kriegstein and Zhang […]

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A single-cell atlas of the normal and malformed human brain vasculature

Cerebrovascular diseases are a leading cause of death and neurologic disability. Further understanding of disease mechanisms and therapeutic strategies requires a deeper knowledge of cerebrovascular cells in humans. We profiled transcriptomes of 181,388 cells to define a cell atlas of the adult human cerebrovasculature, including endothelial cell molecular signatures with arteriovenous segmentation and expanded perivascular […]

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Rebus Bio Continues Expansion of Industry-leading Spatial Omics Platform with Breakthrough High-Plex Technology

SANTA CLARA, CA and STOCKHOLM – Dec. 8, 2021 – Rebus Biosystems Inc, (“Rebus Bio”, “Rebus”), an Illumina Ventures-backed life science technology company creating revolutionary tools to advance spatial omics research, today announced that it has acquired the IP and related assay assets of EEL Transcriptomics AB, a privately-held company focused on high-plex spatial transcriptomics with single-cell resolution. Terms […]

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Mapping the Elusive: Analysis Of Cellular Expression Using the Esper as a Method for Detailed Tissue Mapping and Structural Patterns Recognition

Brett Cook, PhD, Senior Product Manager at Rebus provides an overview of the Esper system. Marcos Otero-Garcia, PhD, Senior Scientist at Rebus, compares mouse disease models of neurodegeneration with the Esper. (11:52) Simone Codeluppi, PhD, Principal Scientist of Bioinformatics, discusses spatial organization of cell types in the mouse cortex revealed by multiplexed single-molecule fluorescent in […]

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Rebus Biosystems Appoints World-leading Researchers to Scientific Advisory Board

SANTA CLARA, CA – Nov. 02, 2021 – Rebus Biosystems Inc, (“Rebus Bio”, “Rebus”), an Illumina Ventures-backed life science technology company creating revolutionary tools to advance spatial omics research, today announced that Drs. Arul Chinnaiyan, MD, PhD and Sten Linnarsson, PhD, have been appointed to the Company’s Scientific Advisory Board (SAB). The two globally recognized scientific advisers bring a […]

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Illumina Ventures Closes $325 Million Fund

San Francisco – Sept. 20, 2021 – Illumina Ventures, an independently-managed, healthcare-focused venture firm, announced today the closing of its second investment fund with total commitments of $325 million, bringing its total capital under management to $560 million. The latest fund is anchored by Illumina, Inc. (Nasdaq: ILMN), with the majority of the total committed capital […]

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An atlas of cortical arealization identifies dynamic molecular signatures

The human brain is subdivided into distinct anatomical structures, including the neocortex, which in turn encompasses dozens of distinct specialized cortical areas. Early morphogenetic gradients are known to establish early brain regions and cortical areas, but how early patterns result in finer and more discrete spatial differences remains poorly understood. Here we use single-cell RNA […]

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Rebus Biosystems Welcomes Danilo Tait as VP Commercial Operations, EMEA

SANTA CLARA, CA – Rebus Biosystems Inc, (“Rebus Bio”, “Rebus”), an Illumina Ventures-backed life science technology company creating revolutionary tools to advance spatial omics research, today announced Danilo Tait as the newest member of its leadership team. Tait, who holds a PhD in molecular biology from the Max-Planck Institute for Molecular Genetics and an MBA from SMC University in […]

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Quantification of gene expression changes in mouse disease models using a high-throughput spatial omics platform

Batch effects due to technical variability are a major problem in single cell transcriptomics. Spatial methods are no exception – their low throughput requires high numbers of technical replicates, reducing the statistical power needed to quantify differential gene expression across experimental conditions. To overcome this problem, we took advantage of the large imaging area of […]

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Rebus Biosystems Continues Rapid Expansion of Scientific Team

SANTA CLARA, CA – Rebus Biosystems, Inc., (“Rebus Bio”), an Illumina Ventures-backed life science technology company creating revolutionary tools to advance spatial omics research, today announced Tarif Awad, a highly experienced technical and commercial leader within the world of life sciences, has joined Rebus Bio as VP Scientific Affairs. “Rebus Biosystems has combined powerful Synthetic Aperture Optics microscopy with automated […]

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Quantitative Single-molecule, Single-cell Spatial Data with Subcellular resolution

The Rebus Esper enables analysis of cells in their native tissue contexts at high throughput and provides rapid analysis of biological molecules directly in and across large tissue sections with pristine subcellular detail.  Rebus Biosystems Director of Marketing Erin Davis explains more in this installment of the Spatial Omics webinar series.

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